13/11/2018 Belgium: leader in pharmaceutical innovation and lab of hope for patients worldwide Erik Present, Janssen Stefaan Vancayzeele, Novartis UZA Research Club, 21/2/208

29/6/2017

Belgium, a European leader in pharma 13/11/2018 Belgium, a European leader in pharma 2nd in export of medicines 2nd in R&D spending € 40,7 Bn €2,89 Bn 4th in pharma employment 2nd in R&D employment 35.250 employees 4.472 researchers Weighting based on the relative share of each country in the total EU population

The pharma valley in Belgium 13/11/2018 The pharma valley in Belgium A unique ecosystem of multinational corporations, biotechnological companies and specialist SMEs

Some key figures of the pharmaceutical sector in Belgium (2016)

60.2 % 50.0 % higher education are female 13/11/2018 pharma sector, an innovation-driven sector that recognizes and values … Jobat 28.5.2016 60.2 % higher education 50.0 % are female Four out of ten managers are women, and in R&D the portion of women increases to 60%. Keep scientific knowledge in BE Remain competitive 40 % managerial functions 60% of researchers Sonja Willems, Chair of Board & Catherine Rutten, CEO pharma.be

13/11/2018 pharma companies are considered very attractive and ‘future proof’ employers GSK is voor de 4de keer verkozen als meest aantrekkelijke werkgever van België, op basis van een onderzoek door Randstad bij 15.000 personen. In de top 5 staan nog 3 andere farmaceutische bedrijven: Janssen Pharmaceutica, UCB en Pfizer. Volgens studie Securex (http://www.nieuwsblad.be/cnt/dmf20160511_02283689) : Mensen voelen zich dus aangetrokken tot de sector, en blijven die ook vrij trouw. Een studie van Securex over het personeelsverloop bevestigt dat bijvoorbeeld werknemers er loyaal zijn aan hun werkgever: slechts 3,2 procent van de werknemers verlaten vrijwillig de onderneming in 2014 ten opzichte van 6,6 procent in de totale private sector. In alle bouwstenen scoort GSK duidelijk beter dan het algemeen gemiddelde. Dit wijst op een zeer sterke basis van de employer brand. Voorbeelden van “bouwstenen”: jobinhoud, loonpakket, toekomst, werksfeer, werkzekerheid, aandacht voor gezondheid, opleidingen ... © Jan Denys Randstad Award 2017 ”Most future proof industry” Randstad Award 2016 “Most attractive employer “ 4 pharma companies in top 5 “job content, job security, wages, training possibilities, work climate, career possibilities, attention for health,…” 02/6/2016

13/11/2018 R&D is at the center of all activities of innovative pharma companies…. R&D The patients Extra op de slide: bij patient support: RWE , app’s (ik heb slides over PSPs en voorbeelden van app’s, als je wilt ?) ... Bij productie en distributie: quality control Voorlopig uitgehaald, anders té drukke slide

Production and distribution 13/11/2018 … as Belgian pharmacompanies are active in all phases of the pharmaceutical chain Clinical trials Market Access Production and distribution Brand support Patient support R&D R&D The patients Extra op de slide: bij patient support: RWE , app’s (ik heb slides over PSPs en voorbeelden van app’s, als je wilt ?) ... Bij productie en distributie: quality control Voorlopig uitgehaald, anders té drukke slide

Plenty of opportunities for people with a background in biomedical sciences (incl. physicians) © HR One Group

13/11/2018 Belgium : a lab of hope for patients, worldwide, thanks to our leadership in clinical trials De Tijd 13.5.2016 Clinical trials: critical phase in the development of new medicines Belgium holds 2nd position in Europe (# trials / capita) yearly >1,500 clinical trials beneficial to patients and their physicians, to the scientific community, and to the Belgian economy In many cases, participation in clinical trials is the last hope for patients to extend their life expectancy, improve their quality of life or even have a chance of recovery. Moreover, many Belgian academics have achieved worldwide recognition as scientific leaders precisely thanks to their involvement in such clinical studies. The Belgian hospitals receive several tens of millions of euros per year for participating in clinical trials. De Standaard 9.5.2016

Belgium, #2 in EU in clinical research 13/11/2018 Belgium, #2 in EU in clinical research Belgium holds a remarkable position in the EU, with: Belgium is at the forefront of novel medical techniques, with:

13/11/2018 July 2015 : Pact of the Future, to preserve the Belgian leadership position Pact of the future for the Patient in Belgium Long-term framework 2015-2019 federal government & pharmaceutical industry Four pillars Accelerated access for patients to innovative medicines Predictability in the funding of a sustainable healthcare system Strengthening Belgium’s leadership in R&D Transparency in the interaction between the industry and stakeholders to “hold on to our yellow jersey”

#WijGevenNietOp - #LeCombatContinue

Pharmaceutical Medicine is a medical scientific specialty concerned with discovery development, evaluation registration monitoring and (medical aspects of) marketing of medicines for the benefit of patients and the public health.

3 main careers in Pharmaceutical Medicine Pharmaceutical Physicians working in: Pharmaceutical industry Medicines regulatory bodies Independent research organizations dedicated to the development of new medicines

R & D : Pharmaceutical Company Pipeline

Pharmaceutical Physicians can be involved - in all Phases of the R&D Process - in headquarters as local companies Carrièrekeuzeavond 2017 - KU Leuven – Faculteit Geneeskunde - Leuven – 09.01.2017

Pharmaceutical Company : Global operations Research& Development Marketing & Sales Production & Supply Carrièrekeuzeavond 2017 - KU Leuven – Faculteit Geneeskunde - Leuven – 09.01.2017

Pharmaceutical Company : Local operations Medical Marketing Sales Carrièrekeuzeavond 2017 - KU Leuven – Faculteit Geneeskunde - Leuven – 09.01.2017

Leading to a wide variety of roles and functions Research Functions Clinical Research Physicians Clinical Trial Leaders Clinical Program Leaders Clinical Safety Experts Project Managers Medical Advisors Regulatory Functions Health Economics Business Functions Management Functions Perspectives at: Expert level Managerial level Perspectives at: Global level Local level Carrièrekeuzeavond 2017 - KU Leuven – Faculteit Geneeskunde - Leuven – 09.01.2017

Competences Technical skills (Inter)personal skills Solid scientific and medical knowledge, clinical experience Research and clinical development processes Biostatistics & data management Literature searching, medical writing and communication Regulatory aspects (Inter)personal skills Team orientation Communicative, open minded, creative,… Leadership & management Carrièrekeuzeavond 2017 - KU Leuven – Faculteit Geneeskunde - Leuven – 09.01.2017

More info BeAPP : www.beapp.be BCPM : www.bcpm.be ULB – PharMed : www.pharmed.be Pharma.be : www.pharma.be Carrièrekeuzeavond 2017 - KU Leuven – Faculteit Geneeskunde - Leuven – 09.01.2017

Carrièrekeuzeavond 2017 - KU Leuven – Faculteit Geneeskunde - Leuven – 09.01.2017

Carrièrekeuzeavond 2017 - KU Leuven – Faculteit Geneeskunde - Leuven – 09.01.2017

Carrièrekeuzeavond 2017 - KU Leuven – Faculteit Geneeskunde - Leuven – 09.01.2017

Carrièrekeuzeavond 2017 - KU Leuven – Faculteit Geneeskunde - Leuven – 09.01.2017