Laparoscopic ileocaecal resection versus infliximab for terminal ileitis in Crohn's disease: a randomised controlled, open-label, multicentre trial  Cyriel Y Ponsioen, PhD, E Joline de Groof, PhD, Emma J Eshuis, PhD, Tjibbe J Gardenbroek, PhD, Patrick M M Bossuyt, PhD, Ailsa Hart, PhD, Janindra Warusavitarne, PhD, Christianne J Buskens, PhD, Ad A van Bodegraven, PhD, Menno A Brink, PhD, Esther C J Consten, PhD, Bart A van Wagensveld, PhD, Marno C M Rijk, PhD, Rogier M P H Crolla, MD, Casper G Noomen, MD, Alexander P J Houdijk, PhD, Rosalie C Mallant, PhD, Maarten Boom, MD, Willem A Marsman, PhD, Hein B Stockmann, PhD, Bregje Mol, MSc, A Jeroen de Groof, MD, Pieter C Stokkers, PhD, Geert R D'Haens, PhD, Dr Willem A Bemelman, PhD Karlien Bruin, John Maring, Theo van Ditzhuijsen, Hubert Prins, Jan van den Brande, Paul Kingma, Anna van Geloven, Nanne de Boer, Donald van der Peet, Jeroen Jansen, Michael Gerhards, Janneke van der Woude, Ruud Schouten, Bas Oldenburg, Richard van Hillegersberg, Rachel West, Guido Mannaerts, Marcel Spanier, Ernst Jan Spillenaar Bilgen, Rob Lieverse, Edwin van der Zaag, Annekatrien Depla, Arnold van de Laar, Clemens Bolwerk, Hans Brouwer, Nofel Mahmmod, Eric Hazebroek, Juda Vecht, Robert Pierik, Gerard Dijkstra, Sijbrand Hofker, Tessa Uiterwaal, Quirijn Eijsbouts, Liekele Oostenbrug, Meindert Sosef, Djuna Cahen, Sjoerd van der Werff, Andreas Marinelli, Job Peters, Huib Cense, Nynke Talstra, Pritesh Morar Cyriel Y Ponsioen, PhD, E Joline de Groof, PhD, Emma J Eshuis, PhD, Tjibbe J Gardenbroek, PhD, Patrick M M Bossuyt, PhD, Ailsa Hart, PhD, Janindra Warusavitarne, PhD, Christianne J Buskens, PhD, Ad A van Bodegraven, PhD, Menno A Brink, PhD, Esther C J Consten, PhD, Bart A van Wagensveld, PhD, Marno C M Rijk, PhD, Rogier M P H Crolla, MD, Casper G Noomen, MD, Alexander P J Houdijk, PhD, Rosalie C Mallant, PhD, Maarten Boom, MD, Willem A Marsman, PhD, Hein B Stockmann, PhD, Bregje Mol, MSc, A Jeroen de Groof, MD, Pieter C Stokkers, PhD, Geert R D'Haens, PhD, Dr Willem A Bemelman, PhD Karlien Bruin, John Maring, Theo van Ditzhuijsen, Hubert Prins, Jan van den Brande, Paul Kingma, Anna van Geloven, Nanne de Boer, Donald van der Peet, Jeroen Jansen, Michael Gerhards, Janneke van der Woude, Ruud Schouten, Bas Oldenburg, Richard van Hillegersberg, Rachel West, Guido Mannaerts, Marcel Spanier, Ernst Jan Spillenaar Bilgen, Rob Lieverse, Edwin van der Zaag, Annekatrien Depla, Arnold van de Laar, Clemens Bolwerk, Hans Brouwer, Nofel Mahmmod, Eric Hazebroek, Juda Vecht, Robert Pierik, Gerard Dijkstra, Sijbrand Hofker, Tessa Uiterwaal, Quirijn Eijsbouts, Liekele Oostenbrug, Meindert Sosef, Djuna Cahen, Sjoerd van der Werff, Andreas Marinelli, Job Peters, Huib Cense, Nynke Talstra, Pritesh Morar  The Lancet Gastroenterology & Hepatology  Volume 2, Issue 11, Pages 785-792 (November 2017) DOI: 10.1016/S2468-1253(17)30248-0 Copyright © 2017 Elsevier Ltd Terms and Conditions

Figure 1 Patient flow diagram *Patient had urgent resection because of sudden deterioration of health. The Lancet Gastroenterology & Hepatology 2017 2, 785-792DOI: (10.1016/S2468-1253(17)30248-0) Copyright © 2017 Elsevier Ltd Terms and Conditions

Figure 2 Quality of life scores (A) Mean IBDQ total score. (B) SF-36 total score. (C) SF-36 physical component score. (D) SF-36 mental component score. Mean scores with 95% CI corrected for baseline difference at 2 and 6 weeks and 3, 6, 9, and 12 months. IBDQ=Inflammatory Bowel Disease Questionnaire. SF-36=Short Form-36. The Lancet Gastroenterology & Hepatology 2017 2, 785-792DOI: (10.1016/S2468-1253(17)30248-0) Copyright © 2017 Elsevier Ltd Terms and Conditions