Erwin Schrodinger, What is Life? The Physical Aspect of the Living Cell, 1944, … Michael P. Murphy and Luke A. J. O’Neill, eds. What is Life? The Next Fifty Years, Cambridge University Press, 1995, 1997.
Towards a Paradigm Shift in Biology Walter Gilbert, Nature 349 (1991) The new paradigm, now emerging, is that all “genes” will be known (in the sense of being resident in databases available electronically), and that the starting point of a biological investigation will be theoretical. An individual scientist will begin with a theoretical conjecture, only then turning to experiments to follow or to test that hypothesis.